Hand began his career in kart racing, starting at the age of 12. Moving up to the Star Mazda Series in 1998, Hand won nine races in the series, winning the rookie of the year award in 1998 and the series championship in 1999.[2]
Following an injury that sidelined him for most of the 2000 season, Hand moved up to the Toyota Atlantic series in 2001, scoring two wins in three years spent in the series, with a best championship finish of third in 2001.[2]
Driving for Chip Ganassi Racing, Hand, along with co-drivers Scott Pruett, Memo Rojas and Graham Rahal, won the 2011 Rolex 24 Hours of Daytonaendurance race at Daytona International Speedway, driving the #01 Riley-BMWDaytona Prototype. The team was set back by a pit road penalty while Hand was driving, however, he was able to recover from the penalty for co-driver Pruett to take the car to victory.[5] The following month the BMW Motorsport team he drove for won the GT class of the 2011 12 Hours of Sebring.[6] Later he joined the BMW Motorsport factory team at the 24 Hours of Le Mans, where he finished third in the GTE-Pro class driving again a BMW M3. Also in 2011, Hand competed full-time at the Grand-Am Sports Car Challenge for Turner, resulting in runner-up with Michael Marsal as a teammate.
Hand returned to BMW Rahal for the 2012 American Le mans Series season. He again won the GT class at the 12 Hours of Sebring and took three podiums out of seven appearances. Meanwhile, he resulted sixth overall at the 24 Hours of Daytona driving a Ganassi BMW.
In the 2013 ALMS season, the driver got a second-place class finish and two-fourths out of six appearances for BMW Rahal with a BMW Z4 de Rahal. Again he raced for Ganassi at the 24 Hours of Daytona and later the Brickyard Grand Prix at Indianapolis.
As the new United SportsCar Championship launched in 2014, Hand resulted second in the GTLM class at the 24 Hours of Daytona and third at the 12 Hours of Sebring for BMW Rahal.
On October 5, 2021, Rick Ware Racing announced that Hand would make his NASCAR debut in the NASCAR Cup Series race at the Charlotte Motor Speedway Roval driving the No. 52.[9] Hand started 36th and finished in 27th. In 2022, Hand drove in all six of the Cup Series road course races driving for Rick Ware in the No. 15. His best finish was 20th at Sonoma and his best starting spot was 9th in Road America. On June 12, 2024, it was announced that Hand would be driving the No. 60 car for RFK Racing in the Chicago Street race.[10] Hand won the second stage in that race for his first career stage win in the NASCAR Cup Series. Hand led 7 laps and almost won the race entirely before being passed by eventual race winner Alex Bowman, after which Hand fell back to fourth.
DTM
On December 15, 2011, Hand was announced as one of BMW's factory drivers for the Deutsche Tourenwagen Masters, which saw him compete in the entire 2012 championship, alongside a limited-season American Le Mans Series campaign with BMW Team RLL.[11] He was the first American to have a full-season factory contract in the series since its inception in 1984.[12] In three seasons he had a best race result of 5th at Brand Hatch and a best season result of 12th, both in 2013.