On 23 February 2010 Løkke Rasmussen announced a major reshuffle, which affected all ministers except for Claus Hjort Frederiksen, Birthe Rønn Hornbech and the prime minister himself.
On 8 March 2011 some minor changes were announced in connection with the firing of Birthe Rønn Hornbech from her position as Minister for Integration as a result of a scandal involving the right of citizenship for stateless residents.