As described in a film magazine,[3] when the foster mother of Mazie-Rosie Carden (Martin) marries, she is forced to find another home. She is sent to Hope Mission where she is given a place to stay. A millionaire named West (Joy) is murdered in his home, and Mazie's brother Ben (West) is accused of the crime. Fear of the police drives Mazie to flee to a church where she hides for several days. On Sunday, she is forced to hide in the pulpit and from here she is able to identify the killer through a much damaged coin West had on his person at the time of his murder. With the real murderer brought to justice and her brother free, Mazie is happy. She discovers that she is loved by a young man whom she befriended when he first came to the town, and like a fairy tale they live happily ever after.
Like many American films of the time, Little Miss Optimist was subject to cuts by city and state film censorship boards. The Chicago Board of Censors cut two views of a stamp (the board always cut close-ups of envelopes), and scenes of the murder striking man on his head with a bronze, man striking Carden with the bronze, and two theft scenes.[4]