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Mezepine
Chemical compound
Mezepine
Clinical data
ATC code
None
Identifiers
IUPAC name
3-(6,11-dihydro-5
H
-dibenzo[b,e]azepin-5-yl)-
N
-methylpropan-1-amine
CAS Number
27432-00-4
27229-23-8 (
fumarate
)
27470-75-3 (
oxalate
)
PubChem
CID
3047746
ChemSpider
2310073
UNII
P21N4Z6JHO
CompTox Dashboard
(
EPA
)
DTXSID90181852
Chemical and physical data
Formula
C
18
H
22
N
2
Molar mass
266.388
g·mol
−1
3D model (
JSmol
)
Interactive image
SMILES
c1cc3c(cc1)Cc2c(cccc2)CN3CCCNC
Mezepine
is a
tricyclic antidepressant
(TCA) that was never marketed.
[
1
]
See also
Tricyclic antidepressant
References
^
Triggle DJ (1997).
Dictionary of pharmacological agents
. London: Chapman & Hall.
ISBN
0-412-46630-9
.
v
t
e
Antidepressants
(
N06A
)
Specific
reuptake inhibitors
and/or
receptor modulators
SSRIs
Tooltip Selective serotonin reuptake inhibitors
Citalopram
Escitalopram
Fluoxetine
#
Fluvoxamine
Indalpine
‡
Paroxetine
Sertraline
Zimelidine
‡
SNRIs
Tooltip Serotonin–norepinephrine reuptake inhibitors
Desvenlafaxine
Duloxetine
Levomilnacipran
Milnacipran
Tofenacin
Venlafaxine
NRIs
Tooltip Norepinephrine reuptake inhibitors
Atomoxetine
Reboxetine
Viloxazine
NDRIs
Tooltip Norepinephrine–dopamine reuptake inhibitors
Amineptine
‡
Bupropion
Nomifensine
‡
NaSSAs
Tooltip Noradrenergic and specific serotonergic antidepressants
Mianserin
Mirtazapine
Setiptiline
SARIs
Tooltip Serotonin antagonist and reuptake inhibitors
Etoperidone
Nefazodone
Trazodone
SMS
Tooltip Serotonin modulator and stimulators
Vilazodone
Vortioxetine
Others
Agomelatine
Amisulpride
Dextromethorphan/bupropion
Esketamine
Etryptamine
‡
Gepirone
Indeloxazine
Flupentixol
Ketamine
§
Medifoxamine
‡
Metryptamine
‡
Oxaflozane
‡
Pivagabine
‡
Tandospirone
Teniloxazine
Tianeptine
Tricyclic
and
tetracyclic antidepressants
TCAs
Tooltip Tricyclic antidepressants
Amineptine
‡
Amitriptyline
#
Amitriptylinoxide
Amoxapine
Butriptyline
‡
Clomipramine
#
Demexiptiline
‡
Desipramine
Dibenzepin
Dimetacrine
‡
Dosulepin
Doxepin
Imipramine
Imipraminoxide
‡
Iprindole
‡
Lofepramine
Melitracen
Metapramine
‡
Nitroxazepine
Nortriptyline
Noxiptiline
Opipramol
Pipofezine
Propizepine
‡
Protriptyline
Quinupramine
‡
Tianeptine
Trimipramine
TeCAs
Tooltip Tetracyclic antidepressants
Maprotiline
Mianserin
Mirtazapine
Setiptiline
Others
Tiazesim
Monoamine oxidase inhibitors
Non-selective
Irreversible:
Benmoxin
‡
Iproclozide
‡
Iproniazid
‡
Isocarboxazid
Isoniazid
#
Linezolid
#
Mebanazine
‡
Nialamide
‡
Octamoxin
‡
Phenelzine
Pheniprazine
‡
Phenoxypropazine
‡
Pivhydrazine
‡
Safrazine
‡
Tedizolid
Tranylcypromine
Reversible:
Caroxazone
‡
Mixed:
Bifemelane
MAO
A
Tooltip Monoamine oxidase A
-selective
Reversible:
Eprobemide
Metralindole
Minaprine
‡
Moclobemide
Pirlindole
Tetrindole
Toloxatone
MAO
B
Tooltip Monoamine oxidase B
-selective
Irreversible:
Selegiline
Adjunctive therapies
Atypical antipsychotics
(
aripiprazole
,
brexpiprazole
,
lurasidone
,
olanzapine
,
quetiapine
,
risperidone
)
Buspirone
Lithium
(
lithium carbonate
,
lithium citrate
)
Thyroid hormones
(
triiodothyronine
(T
3
),
levothyroxine
(T
4
))
Miscellaneous
Ademetionine (
SAMe
)
GABAkine
neurosteroids
(
brexanolone
,
zuranolone
)
Hypericum perforatum
(St. John's Wort)
Oxitriptan (
5-HTP
)
Rubidium chloride (RbCl)
Tryptophan
#
WHO-EM
‡
Withdrawn
from market
Clinical trials
:
†
Phase III
§
Never to phase III
v
t
e
Tricyclics
Classes
Acridine
Anthracene
Dibenzazepine
Dibenzocycloheptene
Dibenzodiazepine
Dibenzothiazepine
Dibenzothiepin
Dibenzoxazepine
Dibenzoxepin
Phenothiazine
Pyridazinobenzoxazine
Pyridinobenzodiazepine
Thioxanthene
Antidepressants
(
Tricyclic antidepressants
(TCAs)
)
Amoxapine
Amezepine
Amineptine
Amitriptyline
Amitriptylinoxide
Amoxapine
Aptazapine
Azepindole
Batelapine
Beloxepin
Butriptyline
Cianopramine
Ciclazindol
Cidoxepin
Clomipramine
Cotriptyline
Cyanodothiepin
Demexiptiline
Depramine (balipramine)
Desipramine (desmethylimipramine)
Desmethylclomipramine
Desmethyltrimipramine
Dibenzepin
Dimetacrine
Dosulepin (dothiepin)
Doxepin
Enprazepine
Fantridone
Fluotracen
Hepzidine
Homopipramol
Imipramine
Imipraminoxide
Intriptyline
Iprindole
Ketipramine
Litracen
Lofepramine
Losindole
Loxapine
Maprotiline
Mariptiline
Mazindol
Melitracen
Metapramine
Mezepine
Mirtazapine
Monometacrine
Nitroxazepine
Norbutriptyline
Nordoxepin
Northiaden (nordosulepin)
Nortriptyline (noramitriptyline)
Noxiptiline
Octriptyline
Opipramol
Pipofezine
Pirandamine
Propizepine
Protriptyline
Quinupramine
Spiroxepin
Tandamine
Tampramine
Tianeptine
Tienopramine
Trimipramine
Antihistamines
Azatadine
Bisulepin
Cidoxepin
Clobenzepam
Cyproheptadine
Dacemazine
Deptropine
Desloratadine
Epinastine
Etymemazine
Fenethazine
Hydroxyethylpromethazine
Isopromethazine
Isothipendyl
Ketotifen
Latrepirdine
Loratadine
Mebhydrolin
Mequitazine
Methdilazine
Olopatadine
Oxomemazine
Perlapine
Phenindamine
Pimethixene
Pirolate
Promethazine
Propiomazine
Rupatadine
Thiazinamium
Antipsychotics
Acetophenazine
Alimemazine
Amoxapine
Asenapine
Butaclamol
Butaperazine
Carfenazine (carphenazine)
Carpipramine
Chlorpromazine
Chlorprothixene
Ciclindole
Citatepine
Clocapramine
Clomacran
Clorotepine
Clotiapine
Clozapine
Cyanothepin
Doclothepin
Docloxythepin
Erizepine
Flucindole
Flumezapine
Fluotracen
Flupentixol
Fluphenazine
Gevotroline
Homopipramol
Isofloxythepin
Levomepromazine/Methotrimeprazine
Loxapine
Maroxepin
Meperathiepin
Mesoridazine
Metiapine
Metitepine
Metoxepin
Mosapramine
Naranol
Octomethothepin
Olanzapine
Oxyclothepin
Oxyprothepin
Pentiapine
Peradithiepin
Perathiepin
Perazine
Perphenazine
Periciazine
Pinoxepin
Piperacetazine
Pipotiazine
Piquindone
Prochlorperazine
Promazine
Prothipendyl
Quetiapine
Savoxepin/Cipazoxapine
Sulforidazine
Tenilapine
Thiethylperazine
Thiopropazate
Thioridazine
Thiothixene
Tilozepine
Traboxopine
Trifluoperazine
Triflupromazine
Trifluthepin
Zotepine
Zuclopenthixol
Anticonvulsants
Carbamazepine
Dizocilpine
Eslicarbazepine
Eslicarbazepine acetate
Etazepine
Licarbazepine
Oxcarbazepine
Oxitriptyline
Anticholinergics
Darenzepine
Dipitramine
Nuvenzepine
Pirenzepine
Profenamine
Rispenzepine
Siltenzepine
Telenzepine
Tripitramine
Tropatepine
Zolenzepine
Others
Adosopine
Aminopromazine
Atiprosin
Benzoctamine
Botiacrine
Carvedilol
Cyclobenzaprine
Damotepine
Elanzepine
Fluradoline
Methylene blue
Monatepil
Oxetorone
Pipazethate
P7C3
Pinadoline
Pitrazepin
Pizotifen
Serazapine
Tipindole
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