RPS6KC1

RPS6KC1
Identifiers
Aliases	RPS6KC1, RPK118, RSKL1, S6K-delta-1, S6PKh1, humS6PKh1, ribosomal protein S6 kinase C1
External IDs	OMIM: 617517; MGI: 2443419; HomoloGene: 8244; GeneCards: RPS6KC1; OMA:RPS6KC1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	190,643,967 bp
RNA expression pattern
	n/a
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; supraoptic nucleus; ; granulocyte; ; neural layer of retina; ; muscle of thigh; ; stroma of bone marrow; ; otic vesicle; ; cingulate gyrus; ; saccule; ; yolk sac;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding; phosphatidylinositol binding; kinase activity; lipid binding;
Cellular component	membrane; cytoplasm; endosome; early endosome;
Biological process	protein phosphorylation; signal transduction; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	26750
	320119
	ENSG00000136643
	ENSMUSG00000089872
	Q96S38
	Q8BLK9
NM_001136138; NM_001287218; NM_001287219; NM_001287220; NM_001287221;
	NM_012424
	NM_178775
NP_001129610; NP_001274147; NP_001274148; NP_001274149; NP_001274150;
	NP_036556; NP_001336575; NP_001336576; NP_001336577; NP_001336578; NP_001336579; NP_001336580; NP_001336581; NP_001336582; NP_001336583; NP_001336586; NP_001336587; NP_001336588; NP_001336589; NP_001336590; NP_001336591; NP_001336592; NP_001336593; NP_001336594; NP_001336595; NP_001336596; NP_001336597; NP_001336598; NP_001336599; NP_001336600; NP_001336601
	NP_848890
	Wikidata
View/Edit Human	View/Edit Mouse

Ribosomal protein S6 kinase delta-1 is an enzyme that in humans is encoded by the RPS6KC1 gene.^[4]^[5]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000089872 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang H, Yu L, Mao N, Fu Q, Tu Q, Gao J, Zhao S (Feb 2000). "Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1". Genomics. 61 (3): 314–8. doi:10.1006/geno.1999.5963. PMID 10552933.
^ "Entrez Gene: RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1".

Hayashi S, Okada T, Igarashi N, Fujita T, Jahangeer S, Nakamura S (2002). "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein". J. Biol. Chem. 277 (36): 33319–24. doi:10.1074/jbc.M201442200. hdl:20.500.14094/D1002671. PMID 12077123.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lehner B, Semple JI, Brown SE, Counsell D, Campbell R, Sanderson CM (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Liu L, Yang C, Yuan J, Chen X, Xu J, Wei Y, Yang J, Lin G, Yu L (2005). "RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains". Mol. Cells. 19 (1): 39–45. doi:10.1016/S1016-8478(23)13134-7. PMID 15750338.
Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000089872 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10552933-4] Zhang H, Yu L, Mao N, Fu Q, Tu Q, Gao J, Zhao S (Feb 2000). "Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1". Genomics. 61 (3): 314–8. doi:10.1006/geno.1999.5963. PMID 10552933.

[entrez-5] "Entrez Gene: RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1".

[1]

[2]

[3]

[4]

[5]

RPS6KC1

References

Further reading