The East and West branches both rise in West Marlborough Township, Pennsylvania, near the hamlet of Upland, and flow south through Kennett Square before uniting just north of the Delaware border. The stream enters Delaware near the town of Yorklyn and flows southward through New Castle County, passing through Marshallton. Red Clay Creek empties into White Clay Creek near Stanton,[7] approximately 5 miles (8.0 km) southwest of Wilmington. Ultimately, White Clay Creek enters the Christina River, also near Stanton.[7]
Since 2000, portions of the river, along with other tributaries of White Clay Creek, have been protected as part of the White Clay Creek Wild and Scenic River.
^U.S. Geological Survey. National Hydrography Dataset high-resolution flowline data. The National Map, accessed April 1, 2011
^The U.S. Geological Survey citation and the Boyd, William citation conflict on which is a tributary of the other, White Clay Creek or Red Clay Creek. The text of the article reflects the U.S. Geological Survey information; Boyd indicates that White Clay Creek is a tributary of Red Clay Creek and that it is Red Clay Creek which flows into the Christina (Christiana) River.