The work depicts a scene from the ancient Greekepic the Odyssey, in which the Sirens attempt to use their enchanting song to lure the titular hero Odysseus and his crew towards deadly waters. As per the Odyssey, Odysseus' crew had already blocked their ears to protect themselves from the Sirens' singing, but Odysseus, wanting to hear the Sirens, had ordered his crew to tie him to the mast so that he may have the pleasure of listening without risking himself or his ship.[2]
The most controversial aspect of Waterhouse's painting was his depiction of the Sirens, as it differed greatly from contemporary Victorian era conceptions. While many of the original audience had expected to see the Sirens as mermaid-like nymphs, they were surprised to find them as bird-like creatures with women's heads.[1] However, at the time of initial exhibition, The Magazine of Art critic Marion H. Spielmann noted that the idea of half-bird, half-woman Sirens is supported by depictions of Sirens similar to Waterhouse's on classical Greek vases.[3]