Powell ran for renomination in 1962, he was defeated in the Primary by John Pillsbury who lost the general election to John W. King. Powell made unsuccessful bids for the governorship in 1964, and 1978, and The U. S. Senate in 1966 and 1972. Powell died of natural causes on January 6, 1981, at the age of 65.
Memorials
A street in Hampton Falls is named Governor Powell Drive.