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It was established at Kapchagai in the Turkestan Military District on 22 July 1976. On 3 April 1978 it became a separate unit. In 1983, elements of the brigade temporarily deployed to Cuba.
Soviet-Afghan War
On 15 March 1985, it was moved to Lashkar Gah and fought in the Soviet–Afghan War. The brigade received a zone of responsibility of 1,100 km along the front and 250 km in depth towards Pakistan. Part of the brigade began fighting in April 1985, having stood in the way of caravans of weapons and drugs coming from Pakistan and Iran.
Formed in December 1986, the 411th detachment, deployed in the province of Farah, was responsible for controlling the caravan routes from Iran. In total, the 22nd brigade alone lost 199 troops in Afghanistan and killed more than 5,000 Mujahideen.[2]