The seat is located entirely within the Akatsi Municipality of the Volta Region of Ghana. The constituency shares a boundary with Akatsi North District at the North, at North-East with Ketu-North Municipality, at the East with Keta Municipal Assembly, to the South with the Anlo District and to the West with South Tongu Municipal Assembly, at the North-West id the Agotime-Ziope District.
There was a by-election in February 2012 as Edward Adjaho had been elected Speaker of the Parliament of Ghana at the beginning of the fourth parliament of the Fourth Republic.[5]
The Electoral Commission of Ghana made changes to the constituencies following the national census in 2010. The total number of constituencies increased by 45 from 230 to 275. The Avenor-Ane became the Akatsi South constituency with Akatsi North carved out of it.[7]
^Frazier, Joe (14 November 2015). "Job 600 and Members of Parliament". Graphic Online. Graphic Communications Group Ltd. Retrieved 29 March 2020. Messrs. K.A Gbedema and Nelson Maglo were the first MPs I saw and listened to. The two gentlemen were CPP Members of Parliament for Keta and Avenor respectively.