Anterior inferior cerebellar artery

Anterior inferior cerebellar artery
Anterior inferior cerebellar artery
	The three major arteries of the cerebellum: the SCA, anterior inferior cerebellar artery (AICA), and PICA.
	Diagram of the arterial circulation at the base of the brain (inferior view). AICA is labeled at lower right.
Details
Source	Basilar artery
Branches	Labyrinthine artery
Vein	Inferior cerebellar veins
Supplies	Anteroinferior surface of the cerebellum, the flocculus, middle cerebellar peduncle and inferolateral portion of the pons.
Identifiers
Latin	arteria cerebelli inferior anterior
TA98	A12.2.08.019
TA2	4550
FMA	50544
	Anatomical terminology [edit on Wikidata]

The anterior inferior cerebellar artery (AICA) is one of three pairs of arteries that supplies blood to the cerebellum.

It arises from the basilar artery on each side at the level of the junction between the medulla oblongata and the pons in the brainstem. It has a variable course, passing backward to be distributed to the anterior part of the undersurface of the cerebellum, anastomosing with both the posterior inferior cerebellar (PICA) branch of the vertebral artery and the superior cerebellar artery.

It also gives off the internal auditory or labyrinthine artery in most cases; however, the labyrinthine artery can less commonly emerge as a branch of the basilar artery.

The amount of tissue receiving blood supply from the AICA is variable, depending upon whether the PICA is more or less dominant, but usually includes the anteroinferior surface of the cerebellum, the flocculus, middle cerebellar peduncle and inferolateral portion of the pons.^[1]

Clinical significance

Occlusion of AICA is considered rare, but generally results in a lateral pontine syndrome, also known as AICA syndrome. The symptoms include sudden onset of vertigo, vomiting, nystagmus, dysarthria, falling to the side of the lesion (due to damage to vestibular nuclei), and a variety of same-side features including hemiataxia, loss of all types of sensation of the face (due to damage to the principal sensory trigeminal nucleus), facial paralysis (due to damage to the facial nucleus), and hearing loss and tinnitus (due to damage to the cochlear nuclei).^[2]^[3]^[4] Facial nucleus damage and its resulting paralysis are specific to AICA lesions, and may be the most distinct clinical identifier of this type of stroke before a CT scan or MRI may be obtained.^[5]

Vertigo may sometimes present as an isolated symptom several weeks or months before acute ischemia and cerebral infarction occurs, probably with the meaning of transient ischemia of the inner ear or the vestibular nerve.^[6]

There is also loss of pain and temperature sensation from the contralateral (opposite-side) limbs and trunk, which can lead to diagnostic confusion with lateral medullary syndrome, which also gives rise to "crossed" neurological signs but does not normally cause cochlear symptoms, severe facial palsy or broad facial sensory loss.^[7]

References

^ Jones, Jeremy; Gaillard, Frank. "Anterior inferior cerebellar artery". Radiopaedia.org. Retrieved 31 May 2015.
^ Atkinson WJ (1952). "The effects of occlusion of the anterior inferior cerebellar artery". Ann R Coll Surg Engl. 12 (2): 126–35. PMC 2377605. PMID 13017512.
^ Amarenco, Pierre; Hauw, Jean-Jacques (1990). "Cerebellar Infarction in the Territory of the Anterior and Inferior Cerebellar Artery". Brain. 113: 139–55. doi:10.1093/brain/113.1.139. PMID 2302529.
^ Deschauer M, Georgiadis D, Lindner A (1998). "[Hearing loss as the leading symptom in anterior inferior cerebellar artery infarction]". Fortschr Neurol Psychiatr (in German). 66 (3): 109–12. doi:10.1055/s-2007-995245. PMID 9565760.
^ Le, Tao; Bhushan, Vikas; Sochat, Matthew; Damisch, Kristina; Abrams, Jordan; Kallianos, Kimberly; Boqambar, Humood; Qiu, Connie; Coleman, Caroline, eds. (2021). First aid for the USMLE step 1 2021. First aid series. New York Chicago San Francisco: McGraw Hill. p. 532. ISBN 978-1-260-46752-9.
^ Oas JG, Baloh RW (1992). "Vertigo and the anterior inferior cerebellar artery syndrome". Neurology. 42 (12): 2274–9. doi:10.1212/wnl.42.12.2274. PMID 1461378. S2CID 24078039.
^ Izumi M, Terao S, Sobue G, Koshimura J, Takatsu S, Yokoi Y, Takahashi M, Mitsuma T (1996). "[Clinical features of anterior inferior cerebellar artery territory infarcts--a study of ten patients]". No to Shinkei (in Japanese). 49 (2): 152–6. PMID 9046527.