The people of Apopa, were a part of the department of San Salvador from June 12, 1824, until March 9, 1836, when it transferred to the federal district of the Central American Federation until June 30, 1839, when it again returned to a municipality of the northern district of San Salvador with the dissolution of the Central American Federation.
As a municipality, Apopa by November 14, 1860, had a population of 2194. Its jurisdiction included three farms: The Angel Arrasola, San José and San Nicolás. The latter purchased by the Municipal Corporation. To cooperate in their acquisition, the General President of the Republic Don Gerardo Barrios by act of January 28, 1865, made Apopa head of the northern district with jurisdiction over San Martin, Nejapan and Tonacatepeque. On March 7, 1874, during the administration of Field Marshal Don Santiago Gonzales Apopa was awarded the title of Villa Apopa. In 1878 the district increased with the incorporation of the municipality of El Paisnal. In 1892 Apopa stopped being head of the former district and became part of the new district Tonacatepeque. On June 7, 1921, during the administration of Jorge Meléndez Apopa was conferred the title of the city of Villa Apopa.
