Giese specializes in the bio-organic chemistry and synthesis of radicals in biological systems.[3][4][5] He contributed to the understanding of radical induced DNA cleavage and of the DNA synthesis by ribonucleotide reductase.[6] He discovered that long range charge transfer through DNA and Peptides occurs by a hopping mechanism.[6][7][8] The formation of carbon–carbon bonds by addition of free radicals to alkenes is called the Giese reaction.[9] Giese developed concepts, guidelines, and synthetic applications for the stereochemistry of radical reactions.[10]
^ abcdefghij"curriculum2". chemie1.unibas.ch. 13 June 2020. Archived from the original on 13 June 2020. Retrieved 11 March 2023.{{cite web}}: CS1 maint: unfit URL (link)
^Taylor, Peter, ed. (2002). Mechanism and Synthesis. Royal Society of Chemistry. ISBN978-0-85404-695-9.
^"research2". chemie1.unibas.ch. 13 June 2020. Archived from the original on 13 June 2020. Retrieved 11 March 2023.{{cite web}}: CS1 maint: unfit URL (link)
^ abc"Bernd Giese". American Academy of Arts and Sciences. Retrieved 13 June 2020.
^Giese, Bernd (2000). "Long-Distance Charge Transport in DNA: The Hopping Mechanism". Accounts of Chemical Research. 33 (9): 631–636. doi:10.1021/ar990040b. ISSN0001-4842. PMID10995201.
^Giese, Bernd (1983). "Formation of CC Bonds by Addition of Free Radicals to Alkenes". Angewandte Chemie International Edition in English. 22 (10): 753–764. doi:10.1002/anie.198307531. ISSN0570-0833.
^Curran, Dennis P.; Porter, Ned A.; Giese, Bernd (1995). Stereochemistry of Radical Reactions: Concepts, Guidelines, and Synthetic Applications. doi:10.1002/9783527615230. ISBN978-3-527-29372-8.
^"Mitglieder". Nationale Akademie der Wissenschaften Leopoldina (in German). 25 September 2021. Retrieved 11 March 2023.