Karad served as the deputy mayor of the Aurangabad Municipal Corporation from 1997-1998.[6] He served two terms as mayor of Aurangabad (2000-2001 and 2005-2006).[8] He served as Director of REC Limited from 2018-2020. Karad was elected to the Rajya Sabha in April 2020. He became a member of the Committee on Petroleum and Natural Gas, and the Consultative Committee for the Ministry of Power and Ministry of New and Renewable Energy in June 2020. Karad was appointed as a Minister of State in the Ministry of Finance on 7 July 2021.[6]
Karad provided emergency medical aid to a passenger suffering from vasovagal syncope while flying onboard IndiGo Flight 171 from Delhi to Mumbai on 16 November 2021.[9][10] Karad, and another member of Parliament Subhash Bhamre, again provided emergency medical aid to a passenger while flying onboard Air India Flight 443 from Delhi to Aurangabad on 17 June 2022.[7][11]