Born in Pará de Minas, Minas Gerais, Bruno Sávio joined América Mineiro's youth setup in 2013, after a trial period.[1] On 5 August 2014, after impressing with the under-20s, he renewed his contract until 2017.[2]
Bruno Sávio made his senior debut on 1 February 2015, coming on as a second-half substitute in a 0–0 Campeonato Mineiro away draw against Guarani. He made his Série B debut on 9 May, starting in a 1–1 home draw against Bahia.
Bruno Sávio scored his first professional goal on 3 October 2015, netting a last minute winner in a 2–1 success at Mogi Mirim.
In January 2022, he joined Bolívar and in his debut game against Blooming on 6 February 2022, he scored a hat-trick.
In September 2022, he transferred to Egyptian club Al Ahly.[3] On 28 October 2022, he scored his first goal for Al Ahly in a 2–0 win against Zamalek in the 2021–22 Egyptian Super Cup.[4] Hence, he won his first title ever in his career.