He came from an old New EnglandCongregationalist family of extraordinary wealth. In 1865, he married Julia Clark Mitchell, with whom he had ten children, including Julia Carolyn Weston, mother to the well known chef and Office of Strategic Services operative Julia Child. They lived in a mansion known as Westonholme, in Dalton, Massachusetts. Byron was elected to the Massachusetts State Senate in 1876. Weston was known for his gifts to the community, including the Grace Episcopal Church in his hometown and funds towards the debt incurred for the grading and draining of an athletic field and monies toward upkeep and a grandstand at Williams College. Weston received an honorary M.A. from Williams College in 1886 and the field, still used today, was named Weston Field in his honor. The Weston Paper Company was acquired by Crane Paper known for currency with the Weston brand used for fine stationary.