In this
Portuguese name , the first or maternal
family name is
Pacheco Pais and the second or paternal family name is
dos Reis e Sousa .
Caetano Maria Pacheco Pais dos Reis e Sousa (born 1968)[ 3] is a Portuguese scientist who is a senior group leader at the Francis Crick Institute [ 2] [ 4] [ 5] [ 6] and a professor of Immunology at Imperial College London .[ 7]
Education
Reis e Sousa was educated at Atlantic College in Wales,[ 6] Imperial College London (BSc) and the University of Oxford where he was awarded a Doctor of Philosophy degree in 1992 for research on dendritic cells , and the phagocytosis of antigens by Langerhans cells supervised by Jonathan Austyn .[ 8]
Career and research
After working as a postdoctoral researcher at the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, with Ronald Germain , he joined the Imperial Cancer Research Fund (ICRF) in 1998.[ 9] He headed the Immunobiology Laboratory which became part of the Francis Crick Institute in 2015.[ 9] He is also a professor of Immunology at Imperial College London [ 10] [ 7] and honorary professor at University College London (UCL) and King's College London .[ 9]
Caetano's research centres on the mechanisms involved in sensing infection, cancer and tissue injury.[ 9] He has helped to define the cells and pathways involved in innate immune detection of RNA viruses , fungi and dead cells.[ 9] [ 11] [ 12] [ 13]
Awards and honours
Reis e Sousa was elected a Fellow of the Royal Society (FRS) in 2019, and is also a Fellow of the Academy of Medical Sciences (FMedSci), a member of the European Molecular Biology Organization (EMBO)[ 1] and was made an Officer of the Order of Sant'Iago da Espada by the Government of Portugal in 2009.[ 9] He was awarded the Louis-Jeantet Prize for Medicine in 2017.[ 3]
References
^ a b Anon (2006). "Caetano Reis e Sousa" . people.embo.org . European Molecular Biology Organization.
^ a b Caetano Reis e Sousa publications indexed by Google Scholar
^ a b c d "Caetano REIS E SOUSA" . jeantet.ch . 4 October 2017.
^ "Caetano Reis e Sousa: Immunobiology Laboratory" . crick.ac.uk .
^ "Researchers: Caetano Reis e Sousa" . crick.ac.uk .
^ a b Bashyam, Hema (2008). "Caetano Reis e Sousa: harnessing DC power" . The Journal of Experimental Medicine . 205 (9): 1946–1947. doi :10.1084/jem.2059pi . ISSN 0022-1007 . PMC 2526189 . PMID 18762569 .
^ a b "Professor Caetano Reis e Sousa" . Imperial College London.
^ Reis e Sousa, Caetano Maria Pacheco Pais dos (1992). Phagocytosis of antigens by Langerhans cells (DPhil thesis). University of Oxford. OCLC 863542179 . EThOS uk.bl.ethos.314901 .
^ a b c d e f Anon (2019). "Professor Caetano Reis e Sousa FMedSci FRS" . royalsociety.org . London: Royal Society . Archived from the original on 24 April 2019. One or more of the preceding sentences incorporates text from the royalsociety.org website where: "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License ." --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
^ Caetano Reis e Sousa publications from Europe PubMed Central
^ Diebold, S. S. (2004). "Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA" . Science . 303 (5663): 1529–1531. Bibcode :2004Sci...303.1529D . doi :10.1126/science.1093616 . ISSN 0036-8075 . PMID 14976261 . S2CID 33144196 .
^ Kato, Hiroki; Takeuchi, Osamu; Sato, Shintaro; Yoneyama, Mitsutoshi; Yamamoto, Masahiro; Matsui, Kosuke; Uematsu, Satoshi; Jung, Andreas; Kawai, Taro; Ishii, Ken J.; Yamaguchi, Osamu; Otsu, Kinya; Tsujimura, Tohru; Koh, Chang-Sung; Reis e Sousa, Caetano; Matsuura, Yoshiharu; Fujita, Takashi; Akira, Shizuo (2006). "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses". Nature . 441 (7089): 101–105. Bibcode :2006Natur.441..101K . doi :10.1038/nature04734 . ISSN 0028-0836 . PMID 16625202 . S2CID 2270879 .
^ Pichlmair, A.; Schulz, O.; Tan, C. P.; Naslund, T. I.; Liljestrom, P.; Weber, F.; Reis e Sousa, C. (2006). "RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates" . Science . 314 (5801): 997–1001. Bibcode :2006Sci...314..997P . doi :10.1126/science.1132998 . ISSN 0036-8075 . PMID 17038589 . S2CID 44366096 .
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