On July 29, 2011, the San Francisco 49ers signed Jones to a four-year, $2.13 million contract that includes a signing bonus of $100,000.[4]
Throughout training camp, Jones competed for a roster spot as a backup safety and special teams player against Madieu Williams, Curtis Taylor, Chris Maragos, and Anthony West.[5] Head coach Jim Harbaugh named Jones the third free safety on the depth chart to begin the regular season, behind Dashon Goldson and Madieu Williams.[6]
He made his professional regular season debut in the San Francisco 49ers' season-opening 33–17 victory against the Seattle Seahawks. Jones was inactive as a healthy scratch for three games (Weeks 2–4). On December 4, 2011, Jones recorded a season-high two solo tackles in the 49ers' 26–0 win against the St. Louis Rams in Week 13.[7] He finished his rookie season in 2011 with six solo tackles in 13 games and zero starts.[8] The San Francisco 49ers finished first in the NFC West with a 13–3 record and earned a first round bye. On January 14, 2012, Jones appeared in his first career playoff game and recorded two solo tackles during their 36–32 win against the New Orleans Saints in the NFC Wildcard Game. The following week, he made one solo tackle as the 49ers lost 20–17 to the New York Giants in the NFC Championship Game.[7]
Jones was inactive during the Panthers' Week 3 loss to the New York Giants due to an injury.[12] In Week 8, Jones collected a season-high two solo tackles during a 23-22 loss at the Chicago Bears.[13] Jones finished the season with 14 combined tackles (ten solo) in 15 games and zero starts.[8]
His first two years with the team his role was exclusively special teams, but started playing nickel corner and backup free safety in 2014.
On June 18, 2014, Jones signed a two-year contract extension with the Panthers.[14]
On February 7, 2016, Jones was part of the Panthers team that played in Super Bowl 50. In the game, the Panthers fell to the Denver Broncos by a score of 24–10.[16]
On March 7, 2017, Jones signed a two-year contract extension with the Panthers.[17]
On March 11, 2019, Jones signed a two-year contract extension with the Panthers.[18]
The Panthers released Jones on March 16, 2020.[19]
Jones married Briana Lewis on February 18, 2012. They have one son.
Jones is a practicing Christian and a member of the Board of Directors of the Christian Outdoor Alliance. He attends Myers Park Methodist Church in Charlotte, North Carolina.[20]