His career took off in 1963 when he appeared with his first group at the legendary Dalia Club in Budapest. From 1964 they gave regular concerts and were frequently featured on Hungarian Radio and TV. Csaba Deseo's debut abroad was in Bled, Yugoslavia 1966, where he played with János Gonda's Qualiton Ensemble. That same year he played with his own group at the Prague International Jazz Festival and with the combo of guitarist Andor Kovacs at the Warsaw Jazz Jamboree. Csaba Deseo's first album under his own name "Four String Tschaba" was published in 1975 by MPS Records in West Germany. On that Deseo played both violin and viola, his partners were German, British and Swedish musicians. Since then Csaba Deseo has recorded 4 LPs and 6 CDs with Hungarian and foreign musicians.
In 1975 he met the famous ZagrebvibraphonistBosko Petrovic, with whom he has been playing regularly until 2011. He also appears as a guest star in Germany, where he usually solos with the group of Walter Kurowski.