D-lactate dehydrogenase (cytochrome c-553)

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In enzymology, a D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) is an enzyme that catalyzes the chemical reaction

(R)-lactate + 2 ferricytochrome c-553 ${\displaystyle \rightleftharpoons }$ pyruvate + 2 ferrocytochrome c-553

Thus, the two substrates of this enzyme are (R)-lactate and ferricytochrome c-553, whereas its two products are pyruvate and ferrocytochrome c-553.

This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-OH group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is (R)-lactate:ferricytochrome-c-553 2-oxidoreductase. This enzyme participates in pyruvate metabolism.

• Ogata M, Arihara K, Yagi T. "D-Lactate dehydrogenase of Desulfovibrio vulgaris". J. Biochem. Tokyo: 1423–1431.