During this season, Chris dates singer Taylor Swift while Peter becomes an Uber driver ("Chris Has Got a Date, Date, Date, Date, Date"),[2] Quagmire gets hooked on Tinder ("The Dating Game"),[3] and also becomes a gigolo during an airline pilot strike ("American Gigg-olo"). Other episode plots include Brian and Stewie writing songs for kids ("The Boys in the Band"), Chris becoming a star baseball player ("Bookie of the Year"), Rob Gronkowski moving in next to Peter with his party bus ("Gronkowsbees"), a homage to three novels commonly taught in (and, in some cases, banned from) American high school English classes ("High School English"),[1][4] Peter and Lois joining the anti-vaccination movement ("Hot Shots"),[5] Peter meeting the children he never knew he had ("A House Full of Peters"), Chris falling for a Mexican teen mom ("Dearly Deported"), and a fictionalized behind-the-scenes look of the show ("Inside Family Guy").[6]
The season premiere includes a cameo by Vinny (voiced by Tony Sirico), the dog who temporarily replaced Brian in season 12.[7] The season concluded with a one hour broadcast of two episodes.
Sick of how pandering children's music is, Stewie and Brian start their own band, singing children's songs with an adult edge, but Stewie's old flame and acting school partner, Olivia, shows up and tries to sabotage him. Meanwhile, Chris gets a job as Quagmire's personal assistant for his sex life.
Note: This episode was dedicated to Doug Lackey one of the music editors of the show.
When Chris starts showing signs of aggression, Peter and Lois end up discovering that he is a talented baseball pitcher. Peter and the guys immediately start betting on the games, as other betters bet big against Chris after seeing him and then lose huge wagers, but Peter is put into an impossible position when the only way to salvage his title game bets is to have Chris lose on purpose. Meanwhile, Brian and Stewie reunite with Frank Sinatra Jr. to open an Italian restaurant, but the restaurant ends up losing money when Frank begins to give everyone free meals.
Note: This was the last appearance of Frank Sinatra Jr. before he died.
When the local airline pilots go on strike, Quagmire is forced to look for a new job and gets one as a gigolo. But when his clients refuse to pay him, Peter is forced to help him out, and their friendship quickly turns into a prostitute/pimp partnership. Meanwhile, Brian gets a job at a hardware store when Peter takes him off his health insurance, and Stewie goes from trying to get him fired to having to perform impromptu surgery to save Brian's life.
James Woods hosts a special episode that takes a look behind the scenes of Family Guy. Meanwhile, Peter is replaced and pitches his own television series to Fox. The story is a reference to sitcom 8 Simple Rules, where David Spade also joined the cast after the family's father had left the show.
Pop singer Taylor Swift agrees to be Chris' date at his homecoming dance, and even though Chris is kind and charming, she sabotages the relationship and then uses the experience to write another song about how the men in her life mistreat her. Meanwhile, Peter becomes an Uber driver.
While Peter is hiding out in a library to escape the police for crashing into a family's house, he reads three novels that are commonly taught (and sometimes banned) in American high schools: The Great Gatsby, Adventures of Huckleberry Finn, and Of Mice and Men.
Peter tells Tricia Takanawa about Carter's plan to use toxic chemicals in Pawtucket Patriot when Carter buys the brewery. Meanwhile, Brian's driver's license expires, and he gets help from Stewie to renew it.
Peter becomes a mall Santa, and he becomes drunk with power when he learns that he can get away with anything, but the real Santa is mad about this and takes direct action to stop Peter. Meanwhile, Stewie and Brian crash Christmas parties for free food, drama, and women.
Quagmire receives free tickets to fly to San Francisco, and Peter, Cleveland and Joe tag along. Soon after, the guys get into a serious situation when Quagmire's plane gets hijacked, which puts Quagmire's flying skills to the test.
Peter and the guys discover Rob Gronkowski of the New England Patriots moving into the house behind the Griffins, but they soon get annoyed with his lifestyle and partying. Meanwhile, Brian discovers that Stewie is a beekeeper and suggests he sell his honey publicly.
Peter becomes a DJ after he and the guys attempt to start their own podcast, leading to discord and (in Peter's case) deafness. Meanwhile, Brian is forced to move into Stewie's room after Lois gets an allergy.
Peter and the guys form a string quartet, and everyone makes the cut except for Peter, who is kicked out. Meanwhile, Brian becomes Carter's seeing eye dog.
When Quagmire discovers Tinder, Peter, Cleveland and Joe must save him from his soul-sucking hedonism. Meanwhile, Stewie is diagnosed with scoliosis and (briefly) enjoys the benefits of being disabled.
Peter helps Joe solve cases, but he gets irritated when Joe takes all the credit for himself. Meanwhile, Brian and Chris look after Stewie after he gets a concussion while playing football.
Peter opens up his own fattening-foods truck to rebel against Lois' healthy-eating plans and to make some extra cash, but feasting on his own wares has terrible effects on Peter's health. Meanwhile, Meg joins a roller derby team, despite Chris' warnings that it's too dangerous.
Peter gets jealous when Lois upstages him at a Boston Red Sox fantasy baseball camp. Meanwhile, Stewie runs away from home when Meg becomes his babysitter.
When Peter temporarily becomes the high school principal, Meg sees his power as an opportunity to get back at her bullies. Meanwhile, Brian and Stewie open up a bed and breakfast and have to deal with a lot of prostitutes.
When Chris's Mexican girlfriend, Isabella, is deported, he steps up to take care of her twin babies. He eventually enlists his parents and Quagmire to head into Mexico and bring her back to the U.S.
After Lois discovers that Peter was a sperm donor in his youth, Peter's past comes back to him when many of his children unexpectedly come to his house – one of whom wants to usurp his place as Lois' husband.