Giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimetres in diameter.[1]: 672
Signs and symptoms
Giant solitary trichoepithelioma primarily affects the perianal and groin region.[2] They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm.[3]
Diagnosis
Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies.[4]
Treatment
The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap.[4]
Martinez, Carlos Augusto Real; Priolli, Denise Gonçalves; Piovesan, Helenice; Waisberg, Jaques (2004). "Nonsolitary Giant Perianal Trichoepithelioma With Malignant Transformation Into Basal Cell Carcinoma: Report of a Case and Review of the Literature". Diseases of the Colon & Rectum. 47 (5). Ovid Technologies (Wolters Kluwer Health): 773–777. doi:10.1007/s10350-003-0104-8. ISSN0012-3706. PMID15073659.
