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Ineffective erythropoiesis

Ineffective erythropoiesis
SpecialtyHematology

Ineffective erythropoiesis is defined by the expansion of early-stage erythroid precursors driven by erythropoietin, accompanied by the apoptosis of late-stage precursors. This mechanism is principally responsible for the anemia seen in acquired conditions such as certain subtypes of myelodysplastic syndrome (MDS) and inherited disorders such as β-thalassemia, inherited sideroblastic anemias, as well as congenital dyserythropoietic anemias.[1]

See also

References

  1. ^ Cazzola, Mario (21 April 2022). "Ineffective erythropoiesis and its treatment". Blood. 139 (16): 2460–2470. doi:10.1182/blood.2021011045. ISSN 1528-0020. PMID 34932791.

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