She was an assistant United States attorney of the Criminal Division for the U.S. Attorney's Office of the District of Arizona from 1975 to 1979. She was a trial attorney of the Antitrust Division of U.S. Department of Justice in Los Angeles in 1979. She was an assistant United States attorney of the Criminal Division for the U.S. Attorney's Office of the Central District of California from 1979 to 1981. She was in private practice of law in San Diego, California from 1981 to 1984. She was a judge on the San Diego County Superior Court from 1991 to 1992.
On August 23, 2010 Gonzalez sided with Trump University in Makaeff vs. Trump University by allowing the countersuit by Trump University for defamation against Makaeff. Gonzalez's decision was unanimously overturned by the Ninth Circuit Court of Appeal on April 17, 2013.