He became President of Carnegie Mellon in 1997. During his first month of his presidency, he oversaw the removal of a stand of trees to build the Purnell Center for the Arts. He was shocked that there were no student protests against the act.
"I'm worried that our undergraduates can be so focused on preparing for their careers that they fail to develop a sense of and passion for what else is important to them."[2] –Jared Cohon, 1997 copy of The Thistle, Carnegie Mellon's now defunct yearbook
Cohon stepped down from his position as President of Carnegie Mellon in 2013 and returned to the faculty as a University Professor in the Departments of Civil and Environmental Engineering and Engineering and Public Policy and director of the Wilton E. Scott Institute for Energy Innovation. In 2014, Carnegie Mellon announced that the University Center would be renamed in honor of President Cohon and will be called the Cohon University Center.[3]
Cohon was elected a member of the National Academy of Engineering (2012) for contributions to environmental systems analysis and national policy and leadership in higher education.
Cohon died on March 16, 2024, at the age of 76.[4]