Padalecki won Fox Broadcasting's 1999 "Claim to Fame Contest"; he subsequently appeared at the Teen Choice Awards, where he met an agent.[5] His first role was a minor role in the 1999 film A Little Inside. In 2000, he was cast as Dean Forester on the television series Gilmore Girls, a role he played until 2005. Throughout the early 2000s, he appeared in several made-for-television films, including Silent Witness, Close to Home and the Disney Channel Original Movie A Ring of Endless Light.[6][7]
Padalecki had an uncredited role as a high school bully in 2003's comedy Cheaper by the Dozen, which he played after being asked by fellow actor and friend Tom Welling, who played Charlie Baker, and the director of the movie, who wanted someone larger than Charlie to pick on him. Padalecki originally auditioned for Welling's role, but gave it up in order to film a pilot titled Young MacGyver which was never picked up.[8]
Also in 2005, Padalecki was cast as Sam Winchester on the WB series, Supernatural. The show ended in 2020, after fifteen seasons, making it the longest-running North American sci-fi series in history.[10]
In 2007, Jared served as the host of MTV's horror reality series, Room 401, which was discontinued after only eight episodes due to poor ratings.[11]
He also had the lead role in the 2009 version of Friday the 13th as Clay Miller, a character who heads out to Camp Crystal Lake in search of his sister who has gone missing.[12]
In September 2019, Padalecki was announced as the title role in Walker, a reboot series of Walker, Texas Ranger in development at The CW.[13][14] The reboot was ordered to series in January 2020[15] and premiered in January 2021.[16] The series was cancelled in 2024 after four seasons.[17] A month later, Padalecki agreed to guest star on The Boys, the Amazon Prime Video superhero drama helmed by Supernatural creator, Eric Kripke.[18] In August 2024, it was announced that Padalecki would join the cast of Fire Country for a three episode guest stint with the possibility of headlining a spinoff.[19]
In March 2015, Padalecki launched his Always Keep Fighting campaign through Represent.com. His first campaign raised funds for To Write Love On Her Arms, which supports people struggling with depression, addiction, self-injury and suicide. The cause is particularly close to Padalecki, who has been candid about his own struggles with depression.[27] For the second campaign in the Always Keep Fighting series in April 2015, Padalecki partnered with co-star Jensen Ackles to release a shirt featuring both of their faces, to benefit their newly formed joint charitable fund. Over 70,000 shirts were sold.[28][29] Later, Padalecki launched a third campaign selling a further 40,000 shirts.[30]
During San Diego Comic-Con 2015, more than 6,000 fans surprised Padalecki at the Supernatural panel by holding up candles for him, after having revealed his battle with depression earlier in the year.[31]
^"Schwan Duo Interpretation"(PDF). The H.B. Mitchell Trophy. National Forensic League. p. 5. Archived from the original(PDF) on September 10, 2008. Retrieved March 31, 2007.
^Keith, Amy Elisa (November 29, 2005). "Celebrity Q&A: Jared Padalecki". People Magazine. Time-Warner. Archived from the original on November 25, 2020. Retrieved November 29, 2006.