He received his education at the University of Leuven, where he earned doctorates in natural sciences (1884) and medicine (1887). From 1884 to 1887 he worked as a préparateur in the laboratory of physiology under Ernest Masoin. Afterwards, he travelled to Berlin, where he spent three years as an assistant to Emil Heinrich Du Bois-Reymond.[1] In 1891 he was named professor of pharmacodynamics and general therapeutics at the University of Ghent. Here, he founded a laboratory for experimental pharmacology and therapeutics.[2] He was rector of the university in 1923-1924.[3]
With German neurophysiologistJohannes Gad, he published a textbook on physiology titled Kurzes Lehrbuch der Physiologie des Menschen. Also, he translated into French, Ewald and Munk's manual of dietetics as Alimentation de l'homme normal et de l'homme malade, traité de diététique a l'usage des médecins.[4] In 1895, with French physiologist Eugène Gley, he founded the journal Archives Internationales de Pharmacodynamie et de Thérapie.[5]