Juvenília is located on the Rio Carinhanha, which forms the boundary with the state of Bahia. It is the most northerly municipality in the state of Minas Gerais and is farther north than Brasília and Itabuna in the state of Bahia. It is connected to Montalvânia by a dirt road.
The economy is based on agriculture with emphasis on cattle raising. There were 27,000 head in 2006. The main agricultural crops were cotton, rice, corn, manioc, sugarcane, and mamona—castor oil plant. The GDP was R$17,275,000 in 2005.
This municipality is extremely isolated from major population centers and suffers from drought and poor soils. It is one of the poorest in the state and in the country.