KDM3B

KDM3B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4C8D
Identifiers
Aliases	KDM3B, 5qNCA, C5orf7, JMJD1B, NET22, lysine demethylase 3B, DIJOS
External IDs	OMIM: 609373; MGI: 1923356; HomoloGene: 41145; GeneCards: KDM3B; OMA:KDM3B - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	138,437,028 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	34,971,713 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; glutes; ; monocyte; ; caput epididymis; ; gastric mucosa; ; mucosa of ileum; ; gastrocnemius muscle; ; tibialis anterior muscle; ; saphenous vein;
	Top expressed in
	tail of embryo; ; neural layer of retina; ; genital tubercle; ; granulocyte; ; tibiofemoral joint; ; ventricular zone; ; renal corpuscle; ; right ventricle; ; thymus; ; corneal stroma;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; antioxidant activity; dioxygenase activity; metal ion binding; histone demethylase activity; transcription cis-regulatory region binding; chromatin DNA binding; histone H3-methyl-lysine-9 demethylase activity;
Cellular component	chromatin; nucleus; nucleoplasm;
Biological process	cellular oxidant detoxification; response to cisplatin; transcription, DNA-templated; regulation of transcription, DNA-templated; histone H3-K9 demethylation; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	51780
	277250
	ENSG00000120733
	ENSMUSG00000038773
	Q7LBC6
	Q6ZPY7
	NM_016604
	NM_001081256; NM_029518
	NP_057688
	NP_001074725
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine-specific demethylase 3B is an enzyme that in humans is encoded by the KDM3B gene.^[5]^[6] KDM3B belongs to the alpha-ketoglutarate-dependent hydroxylase superfamily.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120733 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038773 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Katoh M, Katoh M (Jun 2004). "Identification and characterization of JMJD2 family genes in silico". International Journal of Oncology. 24 (6): 1623–8. doi:10.3892/ijo.25.3.759. PMID 15138608.
^ "Entrez Gene: JMJD1B jumonji domain containing 1B".

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