Siegel made her acting debut in the film The Curse of The Black Dahlia, which was released on January 23, 2007.[2] That year she went on to star in Hacia La Oscuridad, which had its world premiere at the Tribeca Film Festival on April 28, 2007.[3] She also appeared in Steam alongside Ruby Dee and Chelsea Handler.[4] In 2008, Siegel appeared in the short film Knocked Down, which was directed by Ted Collins.[5] In 2009, she made her television debut in Ghost Whisperer as Cheryl. In 2010, she appeared in Numb3rs as Rachel Hollander. She then appeared in an episode of Castle. That same year she appeared in the drama-thriller Wedding Day.[6]
In 2013, Siegel appeared in Man Camp.[7] The same year, she appeared in Oculus, a horror film written and directed by Flanagan.[8] The film had its world premiere at the Toronto International Film Festival in September 2013, and was released in April 2014.[9][10] She also appeared in an episode of Mob City. In 2014, she appeared in Demon Legacy.[11]
In November 2015, it was revealed that she and Flanagan would be adapting the young adult novel 13 Days to Midnight into a film.[12]
In 2016, Siegel starred as a deaf-mute woman beset by a killer in the horror-thriller Hush, a film on which she also made her screenwriting debut, co-writing with Flanagan. The film had its world premiere at South by Southwest on March 12, 2016, and was released on Netflix on April 8, 2016.[13][14] In July 2016, she starred in a commercial for Stelara psoriasis medication.[15] That same year, Siegel appeared in Ouija: Origin of Evil, also directed by Flanagan, which was released on October 21, 2016.[16][17]
In 2017, Siegel starred alongside Carla Gugino and Bruce Greenwood in the film adaptation of Stephen King's Gerald's Game, which was also directed by Flanagan.[18] The film was released on September 29, 2017, by Netflix.[19]
Siegel portrayed Erin Greene in Netflix's Midnight Mass, which was written and directed by Flanagan, and co-starred her castmate from The Haunting of Hill HouseHenry Thomas.
In July 2024, she was confirmed to make her directorial debut, as she would direct a segment for V/H/S/Beyond, which was released exclusively on Shudder on October 4, 2024.[23][24]
Personal life
Siegel is Jewish.[25][26] Siegel said in 2008 she is bisexual[27] and had been in relationships with women before.[28] She married director Mike Flanagan in early 2016.[29] They have two children: a son, Cody, and a daughter, Theodora, named after Siegel's character in The Haunting of Hill House. She is stepmother to Flanagan's eldest son from a previous relationship.[30][31]