Mercado was a member of the municipal council of Odense Municipality from 2006 to 2011, and served as the second deputy mayor from 2009 to 2011. From 2013 to 2016 she sat in the municipal council of Frederiksberg Municipality.[1]
She was elected to the Folketing in the 2011 election. On 28 November 2016, she was appointed as Minister for Children and Social Affairs in the Lars Løkke Rasmussen III Cabinet.[2]
Shortly after introducing laws which would prohibit troublesome minority protests in Freetown Christiania. Mai voiced public support for police enforcement action taken against illegal hash stalls in Haderslev. This prompted a local man named Thomas Dall, the nephew of Danish politician Benny Dall to make terroristic death threats against Mai and her entire family on Facebook,[3] a crime for which he was tried, arrested and served time for. Afterwards she left the Folketing.[4]