Wilson started as a true freshman and recorded 34 tackles and 10 passes broken up.[3] He was named preseason third-team All-SEC going into his sophomore year but tore his ACL two games into the season and redshirted the rest of the season.[4] As a redshirt sophomore, he recorded 36 tackles, 2.5 tackles for a loss, 3 interceptions and 2 passes broken up.[5][6]
As a senior, he had a notable incident involving throwing a shoe in a celebratory manner late during a game played on December 12, 2020, against the LSU Tigers, which resulted in an unsportsmanlike conduct penalty that gave LSU a first down. LSU would go on to win the game after kicking a field goal later that drive, beating the Gators 37–34.[7]
Wilson was drafted by the Arizona Cardinals in the fourth round with the 136th overall pick of the 2021 NFL draft.[11] On May 20, 2021, Wilson signed his four-year rookie contract with Arizona.[12] Wilson entered his rookie season in 2021 as a starting cornerback alongside Byron Murphy. He finished the season with 48 tackles, two forced fumbles, and two passes defensed through 14 games and 13 starts.[13]
In Week 7 of the 2022 season, Wilson had a 38-yard interception return for a touchdown, along with three tackles and two pass breakups, in a 42-34 win over the New Orleans Saints, earning NFC Defensive Player of the Week.[14]