Shortly after retiring, Ferrufino started working as a coach, being Vladimir Soria's assistant at Bolívar. In 2006, he moved with Soria to San José, and was named manager of the club in April 2007 after Soria was sacked.
On 30 April 2008, Ferrufino announced his resignation from San José effective after the following match against Blooming on 5 May.[4] In August 2009, he was named Real Mamoré manager,[5] but opted to leave the club in October. Shortly after, he returned to San José.[6]
Sacked by San José on 10 November 2010,[7] Ferrufino was named at the helm of Real Potosí on 23 February 2011.[8] Dismissed by the latter in August, he returned to San José for a third spell in that month.[9]
Ferrufino was relieved of his duties in November 2013, and took over Nacional Potosí the following 18 February.[10] He left the club roughly a year later,[11] and returned to San José on 25 February 2016.[12]
In November 2017, Ferrufino was named in charge of Sport Boys Warnes, but was replaced by César Vigevani the following 25 February.[13] He was appointed manager of Aurora on 8 August 2018,[14] but left by mutual agreement the following 7 April.[15]
Ferrufino returned to Real Potosí on 9 October 2019,[16] but left on 31 December as his contract expired.[17] However, he returned to the club on 25 January 2020 after Walter Grazziosi left, but was still sacked on 20 March.[18]
On 6 April 2021, Ferrufino returned to San José for a fifth spell,[19] but was sacked on 16 May.
Personal life
Ferrufino's son Douglas is also a footballer and a defender.[20]