Michelin tire baby syndrome (also known as Kunze–Riehm syndrome[1] and "folded skin with scarring"[2]: 625 ), is a condition occurring in babies that is characterized by multiple, symmetric, circular skin creases, or bands, on the forearms, lower legs, and often the neck that are present at birth. The creases disappear later in life. They are reminiscent of those of Bibendum, the mascot of the tire manufacturer Michelin, hence the name of the syndrome. Associated abnormalities vary and may include facial dysmorphism, upslanting palpebral fissures, hypertelorism, cleft palate, genital anomalies, mild developmental delay, ureterocele, smooth muscle hamartoma, nevus lipomatosus, Laron syndrome (dwarfism with high growth hormone and low somatomedin activity), and other defects.
Bass HN, Caldwell S, Brooks BS (February 1993). "Michelin tire baby syndrome: familial constriction bands during infancy and early childhood in four generations". Am J Med Genet. 45 (3): 370–2. doi:10.1002/ajmg.1320450318. PMID8434626.
Schnur RE, Herzberg AJ, Spinner N, et al. (February 1993). "Variability in the Michelin tire syndrome. A child with multiple anomalies, smooth muscle hamartoma, and familial paracentric inversion of chromosome 7q". J Am Acad Dermatol. 28 (2 Pt 2): 364–70. doi:10.1016/0190-9622(93)70056-Y. PMID8436660.
