OR3A2

OR3A2
Identifiers
Aliases	OR3A2, OLFRA04, OR17-14, OR17-228, OR228, olfactory receptor family 3 subfamily A member 2
External IDs	MGI: 3030244; HomoloGene: 68262; GeneCards: OR3A2; OMA:OR3A2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	3,386,317 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	74,228,857 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; right testis; ; left testis; ; islet of Langerhans; ; ventricular zone; ; nucleus accumbens; ; sural nerve; ; caudate nucleus; ; granulocyte;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity; signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	sensory perception of chemical stimulus; sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	4995
	258702
	ENSG00000221882
	ENSMUSG00000063116
	P47893
	Q8VFX7
	NM_002551
	NM_146707
	NP_002542
	NP_666918
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 3A2 is a protein that in humans is encoded by the OR3A2 gene.^[5]^[6]^[7]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000221882 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063116 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Glusman G, Clifton S, Roe B, Lancet D (Feb 1997). "Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity". Genomics. 37 (2): 147–60. doi:10.1006/geno.1996.0536. PMID 8921386.
^ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. S2CID 23416814.
^ ^a ^b "Entrez Gene: OR3A2 olfactory receptor, family 3, subfamily A, member 2".

External links

OR3A2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000221882 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063116 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8921386-5] Glusman G, Clifton S, Roe B, Lancet D (Feb 1997). "Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity". Genomics. 37 (2): 147–60. doi:10.1006/geno.1996.0536. PMID 8921386.

[pmid10673334-6] Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. S2CID 23416814.

[entrez-7] "Entrez Gene: OR3A2 olfactory receptor, family 3, subfamily A, member 2".

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OR3A2

See also

References

Further reading

External links