Bandopadhyay was born as Padmavathy Swaminathan on 4 November 1944 at Tirupathi, Andhra Pradesh into a Tamil speaking Iyer family. When Padma was four or five years old, her mother contracted tuberculosis and eventually became bedridden. As a result, Padma's thoughts have been consumed with medical difficulties since she was a small child, and she also took on the role of her mother's primary caretaker while she was still quite young. In addition, her neighbor in the Gole Market neighborhood in New Delhi was Dr. S. I. Padmavati, Professor of Medicine at Lady Hardinge Medical College. Padma has said that her experience with her mother's illness and hospitalization at Safdarjung Hospital, and having a neighbouring lady doctor with the same name as her were early motivations to become a doctor.[1]
She was the first woman to become a Fellow of the Aerospace Medical Society of India and the first Indian woman to conduct scientific research at the North Pole.[5] She is also the first woman Armed Forces officer to have completed the Defence Services Staff College course in 1978.[6] She was the Director General Medical Services (Air) at the Air Headquarters.[7] In 2002, she became the first woman to be promoted to air vice marshal (two-star rank). She subsequently became the first woman air marshal of Indian Air Force. Bandopadhyay is an aviation medicine specialist and a member of the New York Academy of Sciences.[8]