Papuloerythroderma of Ofuji is a rare disorder most commonly found in Japan, characterized by pruritic papules that spare the skinfolds, producing bands of uninvolved cutis, creating the so-called deck-chair sign. Frequently there is associated blood eosinophilia. Skin biopsies reveal a dense lymphohistiocytic infiltrate, eosinophils in the papillary dermis, and increased Langerhans cells (S-100 positive). Systemic steroids are the treatment of choice and may result in long-term remissions.[1]: 57 [2]
^Torchia D, Miteva M, Hu S, Cohen C, Romanelli P (March 2010). "Papuloerythroderma 2009: two new cases and systematic review of the worldwide literature 25 years after its identification by Ofuji et al". Dermatology. 220 (4): 311–320. doi:10.1159/000301915. PMID20339287. S2CID23915213.
^Ofuji S, Furukawa F, Miyachi Y, Ohno S (1984). "Papuloerythroderma". Dermatologica. 169 (3): 125–130. doi:10.1159/000249586. PMID6148269.
