Mantigirdaitis was married twice. The name or origin of the first wife is unknown; they had one son Jonas, who was not active in politics and possibly died young.[2] His second wife was Anna, daughter of Feodor, son of Kaributas and grandson of Grand Duke Algirdas.[1] This marriage was childless. His main estate was in Iwye in present-day Grodno Region, Belarus (it was granted to him in 1434 by Sigismund Kęstutaitis, but it could have been a confirmation of his patrimonial rights).[2] From his second mother-in-law he received Losk (Belarusian: Лоск) and was asked to take care of her other two daughters.[2] Mantigirdaitis had other landholdings near Šalčininkai and Ashmyany.[2]