Proliferating trichilemmal cysts (also known as a pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor)[1] is a cutaneous condition, characterized by proliferations of squamous cells forming scroll-like structures.[1][2]: 678
Signs and symptoms
The tumors, which are typically found in regions like the scalp with a high density of hair follicles, can be solid or solid cystic. Proliferating trichilemmal cyst frequently manifests clinically as a subcutaneous nodule that gradually grows into a big nodular mass. Rapid growth in some cases may be a sign of malignant development into cancer.[3]
Diagnosis
Histologically, Proliferating trichilemmal cysts are distinguished by trichilemmal keratinization, which is the sudden change from nucleated epithelium to anucleated keratinized cells without a granular layer.[4] The differential diagnosis include trichilemmal cyst and Turban tumor.[5]
Treatment
Surgical excision is the treatment of choice for proliferating trichilemmal cysts.[4]
Epidemiology
Proliferating trichilemmal cysts make up 0.1% of all skin tumors.[4] Most patients with these tumors are older women, and 90% of patients with these lesions appear on the scalp.[6]
