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Small nucleolar RNA snoM1

Small nucleolar RNA snoM1
Predicted secondary structure and sequence conservation of snoM1
Identifiers
SymbolsnoM1
RfamRF00293
Other data
RNA typeGene; snRNA; snoRNA; HACA-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000594
PDB structuresPDBe

In molecular biology, Small nucleolar RNA snoM1 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.

M1 is a predicted to belong to the H/ACA box class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines.[1] snoM1 seems to be found exclusively in Drosophila species.

References

  1. ^ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.

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