This section needs expansion. You can help by adding to it. (February 2018)
The highway travels in a southeast-to-northwest direction, but is signed as a north–south highway. It travels between SC 410/SC 9 Bus. in the community of Finklea, through Mullins where it has a concurrency with SC 41 and intersects US 76, Latta where it intersects U.S. Route 301 (US 301) and US 501, to SC 38 south of its interchange with I-95.[4]
South Carolina Highway 73 (SC 73) was a state highway that was established in 1939 from US 301/US 501 in Latta southeast to SC 57 (now SC 41) south-southeast of Fork. In 1942, it was decommissioned and redesignated as SC 573. Today, most of its path is part of SC 917.