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TRPM6

TRPM6
Identifiers
AliasesTRPM6, CHAK2, HMGX, HOMG, HOMG1, HSH, transient receptor potential cation channel subfamily M member 6
External IDsOMIM: 607009; MGI: 2675603; HomoloGene: 9767; GeneCards: TRPM6; OMA:TRPM6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

140803

225997

Ensembl

ENSG00000119121

ENSMUSG00000024727

UniProt

Q9BX84

Q8CIR4

RefSeq (mRNA)

NM_001177310
NM_001177311
NM_017662

NM_153417

RefSeq (protein)

NP_001170781
NP_001170782
NP_060132

NP_700466

Location (UCSC)Chr 9: 74.72 – 74.89 MbChr 19: 18.73 – 18.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119121 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024727 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schlingmann KP, Weber S, Peters M, et al. (2002). "Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family". Nat. Genet. 31 (2): 166–70. doi:10.1038/ng889. PMID 12032568. S2CID 40990544.

Further reading

  • Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. Vol. 704. Berlin: Springer. p. 700. ISBN 978-94-007-0264-6.
  • Chubanov V, Gudermann T, Schlingmann KP (2006). "Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis". Pflügers Arch. 451 (1): 228–34. doi:10.1007/s00424-005-1470-y. PMID 16075242. S2CID 6037803.
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350.
  • Bödding M (2007). "TRPM6: A Janus-like protein". Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology. Vol. 179. pp. 299–311. doi:10.1007/978-3-540-34891-7_18. ISBN 978-3-540-34889-4. PMID 17217065.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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