In 1986, De Jesus made both her stage and television debuts: starring opposite Robert De Niro in the Broadway play Cuba and His Teddy Bear and playing a recurring role on the NBC daytime soap opera Another World.[4] In 1987, De Jesus starred in the short-lived ABC prison drama series, Mariah.[5] She later made guest starring appearances on L.A. Law, Tales from the Darkside and Matlock.
In 2010, De Jesus had a recurring role as Iris Blanco, the mayor of Pine Valley in the ABC soap opera, All My Children. Later in 2010, De Jesus was cast as the head of the police squad on the NBC series Law & Order: Los Angeles, but the role – which had already been changed significantly before De Jesus joined – was changed again and reshot with a different actress after two episodes had been filmed.[8] In 2012 she had a recurring role in the FX crime drama series, Sons of Anarchy.[9] In 2022 she had a recurring role in the Paramount+ psychological thriller Fatal Attraction.[10]
Personal life
De Jesus has been in a relationship with actor Jimmy Smits since 1986. They live together in Los Angeles.[11]