Athletic programs include football, baseball, fastpitch, basketball (men's and women's), soccer (men's and women's), bowling, swimming and diving, volleyball, golf, tennis, track and field, and cheerleading, with talks of forming a lacrosse team.
The school's broadcasting class. Each day the class put together a show of the days announcements. To be in WSCN, students must pass a Beginning Broadcasting class and obtain permission from the teacher. Students also produce music videos, PTVs, Public Service Announcements, and several other projects which are broadcast on the school's television station, and other local television channels.
Computer Graphics
The school's Computer Graphics program offers students the chance to design computer graphics.
Marching Band
The Warren G. Harding "Raider" marching band is the school's band. They participated in the 2004 Macy's Thanksgiving Day Parade. The band was also invited to play in the 65th Pearl Harbor anniversary in Hawaii. The band also received the honor of being invited to play at the 2008 Summer Olympics in Beijing. The "Raider Band" was also invited to march in the national memorial day parade in 2009, and did so in late May 2010. They also participated in the Pittsburgh Celebrate the Season parade in 2007 and 2009. The 2013-14 "Raider Band" participated in the 2014 National Tartan Day Parade in New York City, in which they were the only high school marching band and the largest performing group. In March 2016 the band participated in Chicago's St. Patrick's Day parade. In the Spring of 2018, the band traveled to Virginia to participate in the 75th annual Apple Blossom Parade. The band also went to the 81st Apple Blossom Parade on May 7th, 2024.
Choir
There are various types of choirs at Harding, including the madrigals and new tomorrows where the students dance and sing on stage. Traditional groups include the a cappella choir, the concert choir, and the freshman chorale.
FIRST Robotics
Warren G. Harding Team E.L.I.T.E. 48 (Encouraging Learning In Technology and Engineering) is a FIRST Robotics Competition team. Each year FIRST creates a new game/challenge, and every team has six weeks to design and manufacture a robot to complete the given tasks.
Quizbowl/Academic team
The Warren G. Harding quizbowl team is regularly ranked within the top 100 of the nation. In 2012 the team won the school's first state championship in the activity, led by senior Michael Coates.