After leaving Nebraska, Powers became the head coach at Washington State. One year after he left Nebraska, Powers took his unranked Washington State Cougars into Lincoln and knocked off the fifteenth-ranked Huskers in the season opener at Memorial Stadium.[3][4]
The following year in 1978, Powers became the head coach at Missouri. With the Missouri Tigers, Powers again went to Lincoln with another unranked team and pulled off a victory over the second-ranked Nebraska team. Following that game, it would be another 25 years until 2003 when the Missouri Tigers would again defeat the Nebraska Cornhuskers. During his tenure at Missouri, Powers compiled a 46–33–3 (.579) record, including four straight bowl appearances from 1978 to 1981. His best seasons came in 1980 and 1981, where he posted consecutive 8–4 records. In addition, his Tiger football teams went 3–2 in bowl games, defeating LSU in the 1978 Liberty Bowl, South Carolina in the 1979 Hall of Fame Classic, and Southern Miss in the 1981 Tangerine Bowl. During Powers' tensure, Missouri also played in the 1980 Liberty Bowl, losing to Purdue, and the 1983 Holiday Bowl, losing to a BYU Cougars team led by quarterback Steve Young.
On October 24, 1979, the NCAA's Committee on Infractions publicly reprimanded Missouri for a violation of NCAA Constitution related to a failure to exercise institutional control. The violation was in regard to the use of a fund established outside the university for the purpose of paying Powers for debt he assumed while negotiating to become Missouri's head coach. NCAA regulations require the university's involvement when its coach receives a cash supplement related to duties he is performing on the institution's behalf, and the NCAA found that Missouri had failed to do so.
After a disappointing 3–7–1 season in 1984 that concluded with another loss to rivalKansas, Powers was relieved of his duties.[3]
Death
Powers died on November 2, 2021, in St. Louis, after suffering from Alzheimer's disease.[5]