When his father died in March 1918, William Archer Redmond resigned his Tyrone seat and successfully defended his father's seat of Waterford at the subsequent by-election. Famously he campaigned in his army uniform and wearing a black armband. His victory ended a run of Sinn Féin victories at by-elections and gave a big, albeit temporary, boost to the morale of supporters of the Irish Parliamentary Party. He did not take part in the First Dáil.
In the general election of December 1918, he was re-elected for Waterford City, becoming one of only two Irish Parliamentary Party MPs outside the six counties of Northern Ireland, and he spoke out strongly in the House of Commons against British military policy in Ireland during the Irish War of Independence.
"I was pleased to fight shoulder to shoulder, on the Somme and elsewhere, with my fellow-countrymen from the North of Ireland. We fraternised, and we thought that when we came home we would not bicker again, but that we would be happy in Ireland, with a Parliament for our own native country. We did not want two Irelands at the Front; it was one Ireland, whether we, came from the North or from the South...I feel in common with thousands of my countrymen in Ireland, that I and they have been cheated out of the fruits of our victory. We placed our trust in you and you have betrayed us."
However Redmond alarmed his supporters by supporting a motion of no confidence placed by Labour Party and Fianna Fáil to bring down the Cumann na nGaedheal government, and replace it with a minority Labour Party–National League administration supported from outside by Fianna Fáil. The attempt failed and in the ensuing general election in September 1927, the party won only two seats, including Redmond. The following year the National League was dissolved and in 1931 Redmond joined Cumann na nGaedheal. He died in April 1932. No by-election was held for the vacancy. His wife Bridget Redmond was elected as a Cumann na nGaedheal TD for Waterford at the 1933 general election.