Ardem Patapoutian
Ardem Patapoutian (Bahasa Armenia : Արտեմ Փաթափութեան ; lahir 2 Oktober 1967)[ 1] ialah ahli biologi molekul , ahli sains saraf Amerika dan penerima Hadiah Nobel .[ 2] Beliau terkenal dengan karyanya dalam mencirikan reseptor PIEZO1, PIEZO2, dan TRPM8 yang mengesan tekanan, mentol , dan suhu. Patapoutian ialah profesor neurosains dan penyelidik Institut Perubatan Howard Hughes di Scripps Research di La Jolla, California. Pada tahun 2021, beliau memenangi Hadiah Nobel dalam Fisiologi atau Perubatan bersama dengan David Julius .[ 3]
Penerbitan terpilih
PIEZO1 + PIEZO2
Coste, B.; Mathur, J.; Schmidt, M.; Earley, T. J.; Ranade, S.; Petrus, M. J.; Dubin, A. E.; Patapoutian, A. (September 2, 2010). "Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels" . Science . American Association for the Advancement of Science (AAAS). 330 (6000): 55–60. Bibcode :2010Sci...330...55C . doi :10.1126/science.1193270 . ISSN 0036-8075 . PMC 3062430 . PMID 20813920 .
Coste, Bertrand; Xiao, Bailong; Santos, Jose S.; Syeda, Ruhma; Grandl, Jörg; Spencer, Kathryn S.; Kim, Sung Eun; Schmidt, Manuela; Mathur, Jayanti; Dubin, Adrienne E.; Montal, Mauricio; Patapoutian, Ardem (February 19, 2012). "Piezo proteins are pore-forming subunits of mechanically activated channels" . Nature . Springer Science and Business Media LLC. 483 (7388): 176–181. Bibcode :2012Natur.483..176C . doi :10.1038/nature10812 . ISSN 0028-0836 . PMC 3297710 . PMID 22343900 .
PIEZO2
Ranade, Sanjeev S.; Woo, Seung-Hyun; Dubin, Adrienne E.; Moshourab, Rabih A.; Wetzel, Christiane; Petrus, Matt; Mathur, Jayanti; Bégay, Valérie; Coste, Bertrand; Mainquist, James; Wilson, A. J. (December 2014). "Piezo2 is the major transducer of mechanical forces for touch sensation in mice" . Nature (dalam bahasa Inggeris). 516 (7529): 121–125. Bibcode :2014Natur.516..121R . doi :10.1038/nature13980 . ISSN 1476-4687 . PMC 4380172 . PMID 25471886 .
Woo, Seung-Hyun; Ranade, Sanjeev; Weyer, Andy D.; Dubin, Adrienne E.; Baba, Yoshichika; Qiu, Zhaozhu; Petrus, Matt; Miyamoto, Takashi; Reddy, Kritika; Lumpkin, Ellen A.; Stucky, Cheryl L.; Patapoutian, Ardem (April 6, 2014). "Piezo2 is required for Merkel-cell mechanotransduction" . Nature . Springer Science and Business Media LLC. 509 (7502): 622–626. Bibcode :2014Natur.509..622W . doi :10.1038/nature13251 . ISSN 0028-0836 . PMC 4039622 . PMID 24717433 .
Rujukan
Pautan luar
1901–1925 1926–1950 1951–1975 1976–2000 2001–kini
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