Bacilolizin

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Bacilolizin
Bacilolizin
Identifikatori
EC broj	3.4.24.28
CAS broj	9080-56-2
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Bacilolizin (EC 3.4.24.28, Bacillus metaloendopeptidaza, Bacillus subtilis neutralna proteinaza, anilozim P 10, Bacillus metaloproteinaza, Bacillus neutralna proteinaza, megateriopeptidaza) je enzim.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]^[9]^[10] Ovaj enzim katalizuje sledeću hemijsku reakciju

Slično, ali ne identično dejstvo sa termolizinom

Varijante ovog enzima su prisutne u vrstama Bacillus bakterija

Reference

^ Morihara, K., Tsuzuki, H. and Oka, T. (1968). „Comparison of the specificities of various neutral proteinases from microorganisms”. Arch. Biochem. Biophys. 123: 572—588. PMID 4967801.
^ Millet, J. & Acher, R. (1969). „Spécificité de la mégatériopeptidase: une amino-endopeptidase à caractère hydrophobe”. Eur. J. Biochem. 9: 456—462. PMID 4980359.
^ Feder, J., Keay, L., Garrett, L.R., Cirulis, N., Moseley, M.H. and Wildi, B.S. (1971). „Bacillus cereus neutral protease”. Biochim. Biophys. Acta. 251: 74—78. PMID 5002444.
^ Holmquist, B. & Vallee, B.L. (1976). „Esterase activity of zinc neutral proteases”. Biochemistry. 15: 101—107. PMID 2276.
^ Vasantha, N., Thompson, L.D., Rhodes, C., Banner, C., Nagle, J. and Filpula, D. (1984). „Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein”. J. Bacteriol. 159: 811—819. PMID 6090391.
^ Yang, M.Y., Ferrari, E. and Henner, D.J. (1984). „Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation”. J. Bacteriol. 160: 15—21. PMID 6090407.
^ Takagi, M., Imanaka, T. and Aiba, S. (1985). „Nucleotide sequence and promoter region for the neutral protease gene from Bacillus stearothermophilus”. J. Bacteriol. 163: 824—831. PMID 2993245.
^ Sidler, W., Niederer, E., Suter, F. and Zuber, H. (1986). „The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase”. Biol. Chem. Hoppe-Seyler. 367: 643—657. PMID 3092843.
^ Pauptit, R.A., Karlson, R., Picot, D., Jenkins, J.A., Niklaus-Reimer, A.-S. and Jansonius, J.N. (1988). „Crystal structure of neutral protease from Bacillus cereus refined at 3.0 Å resolution and comparison with the homologous but more thermostable enzyme thermolysin”. J. Mol. Biol. 199: 525—537. PMID 3127592.
^ Stoeva, S., Kleinschmidt, T., Mesrob, B. and Braunitzer, G. (1990). „Primary structure of a zinc protease from Bacillus mesentericus strain 76”. Biochemistry. 29: 527—534. PMID 2302386.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Bacillolysin на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Morihara, K., Tsuzuki, H. and Oka, T. (1968). „Comparison of the specificities of various neutral proteinases from microorganisms”. Arch. Biochem. Biophys. 123: 572—588. PMID 4967801.

[2] Millet, J. & Acher, R. (1969). „Spécificité de la mégatériopeptidase: une amino-endopeptidase à caractère hydrophobe”. Eur. J. Biochem. 9: 456—462. PMID 4980359.

[3] Feder, J., Keay, L., Garrett, L.R., Cirulis, N., Moseley, M.H. and Wildi, B.S. (1971). „Bacillus cereus neutral protease”. Biochim. Biophys. Acta. 251: 74—78. PMID 5002444.

[4] Holmquist, B. & Vallee, B.L. (1976). „Esterase activity of zinc neutral proteases”. Biochemistry. 15: 101—107. PMID 2276.

[5] Vasantha, N., Thompson, L.D., Rhodes, C., Banner, C., Nagle, J. and Filpula, D. (1984). „Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein”. J. Bacteriol. 159: 811—819. PMID 6090391.

[6] Yang, M.Y., Ferrari, E. and Henner, D.J. (1984). „Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation”. J. Bacteriol. 160: 15—21. PMID 6090407.

[7] Takagi, M., Imanaka, T. and Aiba, S. (1985). „Nucleotide sequence and promoter region for the neutral protease gene from Bacillus stearothermophilus”. J. Bacteriol. 163: 824—831. PMID 2993245.

[8] Sidler, W., Niederer, E., Suter, F. and Zuber, H. (1986). „The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase”. Biol. Chem. Hoppe-Seyler. 367: 643—657. PMID 3092843.

[9] Pauptit, R.A., Karlson, R., Picot, D., Jenkins, J.A., Niklaus-Reimer, A.-S. and Jansonius, J.N. (1988). „Crystal structure of neutral protease from Bacillus cereus refined at 3.0 Å resolution and comparison with the homologous but more thermostable enzyme thermolysin”. J. Mol. Biol. 199: 525—537. PMID 3127592.

[10] Stoeva, S., Kleinschmidt, T., Mesrob, B. and Braunitzer, G. (1990). „Primary structure of a zinc protease from Bacillus mesentericus strain 76”. Biochemistry. 29: 527—534. PMID 2302386.

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