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Kancerni prokoagulant

Kancerni prokoagulant

Identifikatori

Baze podataka

NiceZyme pregled

metabolički put

Strukture PBP

RCSB PDB PDBe PDBj PDBsum

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Kancerni prokoagulant (EC 3.4.22.26, Cancer procoagulant) je enzim.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Specifično razlaganje Arg-Ile veze u faktoru X čime se formira faktor Xa

Ovaj enzim izražavaju samo maligne i fetusne ćelije

Reference

^ Falanga, A. & Gordon, S.G. (1985). „Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue”. Biochemistry. 24: 5558—5567. PMID 3935163.
^ Falanga, A., Shaw, E., Donati, M.B., Consonni, R., Barbui, T. and Gordon, S. (1989). „Inhibition of cancer procoagulant by peptidyl diazomethyl ketones and peptidyl sulfonium salts”. Thromb. Res. 54: 389—398. PMID 2772865.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Cancer+procoagulant на US National Library of Medicine Medical Subject Headings (MeSH)

п р у Proteaze: cisteinske proteaze (EC 3.4.22)
Kaspaza	Kaspaza 1 Kaspaza 2 Kaspaza 3 Kaspaza 4 Kaspaza 5 Kaspaza 6 Kaspaza 7 Kaspaza 8 Kaspaza 9 Kaspaza 10 Kaspaza 12 Kaspaza 13 Kaspaza 14
Izvedeni iz voća	Papain Fikain Bromelain Aktinidain
Kalpain	CAPN1 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPNS1 CAPNS2
Katepsin	B C F H K L1/L2 O S W Z
Drugi	Klostripain Prokoagulant kancera Separaza Autofagin Kruzipain

п р у Enzimi
Teme	Aktivno mesto Alosterna regulacija Mesto vezivanja Katalitički perfektan enzim Koenzim Kofaktor Kooperativnost EC broj Enzimska kataliza Inhibicija enzima Enzimska kinetika Lajnviver—Berkov dijagram Mihaelis—Mentenina kinetika Spisak enzima
Tipovi	EC1 Oksidoreduktaze /spisak EC2 Transferaze /spisak EC3 Hidrolaze /spisak EC4 Lijaze /spisak EC5 Izomeraze /spisak EC6 Ligaze /spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6

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