Share to: share facebook share twitter share wa share telegram print page

Ketoprofen

Ketoprofen
Klinički podaci
Prodajno imeActron, Alrheumat, Alrheumun, Capisten
Drugs.comMonografija
Način primeneOralno
Farmakokinetički podaci
Poluvreme eliminacije1,1-4 h
IzlučivanjeRenalno (80%)
Identifikatori
CAS broj22071-15-4 ДаY
ATC kodM01AE03 (WHO), M02AA10
PubChemCID 3825
DrugBankDB01009 ДаY
ChemSpider3693 ДаY
KEGGC01716 ДаY
ChEBICHEBI:6128 ДаY
ChEMBLCHEMBL571 ДаY
Hemijski podaci
FormulaC16H14O3
Molarna masa254,281
  • CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
  • InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) ДаY
  • Key:DKYWVDODHFEZIM-UHFFFAOYSA-N ДаY
Fizički podaci
Tačka topljenja94 °C (201 °F)

Ketoprofen je organsko jedinjenje, koje sadrži 16 atoma ugljenika i ima molekulsku masu od 254,281 Da.[1][2][3][4]

Osobine

Osobina Vrednost
Broj akceptora vodonika 3
Broj donora vodonika 1
Broj rotacionih veza 4
Particioni koeficijent[5] (ALogP) 3,4
Rastvorljivost[6] (logS, log(mol/L)) -4,4
Polarna površina[7] (PSA, Å2) 54,4

Reference

  1. ^ Kantor TG: Ketoprofen: a review of its pharmacologic and clinical properties. Pharmacotherapy. 1986 May-Jun;6(3):93-103. PMID 3526298
  2. ^ Mazieres B: Topical ketoprofen patch. Drugs R D. 2005;6(6):337-44. PMID 16274258
  3. ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709 Слободан приступ. PMID 21059682. doi:10.1093/nar/gkq1126.  уреди
  4. ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 Слободан приступ. PMID 18048412. doi:10.1093/nar/gkm958.  уреди
  5. ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o. 
  6. ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.  уреди
  7. ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.  уреди

Literatura

Spoljašnje veze


Molimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).

Read other articles:

Sharron Davies

Sharron Davies FöddSharron Elizabeth Davies1 november 1962[1] (61 år)Plymouth, StorbritannienMedborgare iStorbritannien[2]Utbildad vidKelly CollegePlymstock School SysselsättningTV-programledare, simmareMakeDerek Redmond(g. 1994–2000, skilsmässa)UtmärkelserRiddare av Brittiska imperieordenRedigera Wikidata Sharron Davies Simning, damer Nation: Storbritannien Olympiska spel Silver Moskva 1980 400 m medley Sharron Davies, född 1 november 1962 i Plymouth i Devon, är en br...

 

2017 Tour de Romandie

Cycling race Cycling race 2017 Tour de Romandie2017 UCI World Tour, race 19 of 37Race detailsDates25–30 April 2017Stages6Distance682.98 km (424.4 mi)Winning time17h 16' 00[1]Results Winner  Richie Porte (AUS) (BMC Racing Team)  Second  Simon Yates (GBR) (Orica–Scott)  Third  Primož Roglič (SLO) (LottoNL–Jumbo) Points  Stefan Küng (SUI) (BMC Racing Team) Mountains  Sander Armée (BEL) (Lotto–Soudal) Youth ...

 

ذراع الصانعة (وشحة)

قرية ذراع الصانعة  - قرية -  تقسيم إداري البلد  اليمن المحافظة محافظة حجة المديرية مديرية وشحة العزلة عزلة بني رزق السكان التعداد السكاني 2004 السكان 283   • الذكور 146   • الإناث 137   • عدد الأسر 45   • عدد المساكن 45 معلومات أخرى التوقيت توقيت اليمن (+3 غرينيت�...

Ehrenburg (Niedersachsen)

Wappen Deutschlandkarte 52.758.699722222222249Koordinaten: 52° 45′ N, 8° 42′ O Basisdaten Bundesland: Niedersachsen Landkreis: Diepholz Samtgemeinde: Schwaförden Höhe: 49 m ü. NHN Fläche: 49,17 km2 Einwohner: 1508 (31. Dez. 2022)[1] Bevölkerungsdichte: 31 Einwohner je km2 Postleitzahl: 27248 Vorwahl: 04275 Kfz-Kennzeichen: DH, SY Gemeindeschlüssel: 03 2 51 015 Adresse der Verbandsverwaltung: Poststr. 1572...

 

Френсіс О'Доннелл

Френсіс О'ДоннеллFrancis Martin O'Donnell Народився 13 березня 1954(1954-03-13) (69 років)ДублінКраїна  ІрландіяДіяльність дипломатВідомий завдяки дипломат системи ООНAlma mater Національний університет ІрландіїЗаклад Організація Об’єднаних НаційТитул БаронПосада Координатор системи ОО...

 

Food Terminal Inc.

Government owned-and-controlled food corporation in the Philippines Food Terminal Incorporated (FTI)FTI Main Building in Arca South, TaguigFormerlyGreater Manila Terminal Food Market (GMTFM)[1][2]TypeGovernment owned and controlled corporation (from 1980)[1]IndustryIndustrial and agricultural enterprisesFoundedApril 30, 1968; 55 years ago (1968-04-30) (as Greater Manila Terminal Food Market)[1][2]March 27, 1974; 49 years a...

Tōkamachi, Niigata

Tōkamachi 十日町市Kota BenderaLambangLocation of Tōkamachi in Niigata PrefectureNegara JepangWilayahChūbuPrefekturNiigataPemerintahan • WalikotaYoshifumi SekiguchiLuas • Total590,39 km2 (22,795 sq mi)Populasi (Januari 1, 2020) • Total50.536 • Kepadatan85,6/km2 (2,220/sq mi)Zona waktuUTC+9 (Japan Standard Time)Simbol kota • PohonFagus crenata• BungaLiliumNomor telepon025-757-3111Alamat3-3 Chitose...

 

Miranda Goeltom

Ini adalah nama Batak Toba, marganya adalah Gultom. Miranda Swaray GoeltomMiranda Swaray GoeltomGubernur Bank IndonesiaPelaksana tugasMasa jabatan17 Mei 2009 – 26 Juli 2009PresidenSusilo Bambang YudhoyonoPendahuluBoedionoPenggantiDarmin Nasution(Sebagai Pelaksana Tugas) Informasi pribadiLahirMiranda Swaray Goeltom19 Juni 1949 (umur 74)Jakarta, IndonesiaKebangsaanIndonesiaSuami/istriErwin Siregar (1978–2003) Oloan Siahaan (m. 2003)Anak2Alma materUniversitas Indonesia Boston U...

 

哈萨克斯坦国家地震观测与研究中心

 哈萨克斯坦政府機構哈萨克斯坦国家地震观测与研究中心Қазақстандық ұлттық сейсмологиялық обсерватория және ғылыми-зерттеу орталығы（哈萨克语）機構概要成立時間1991年前身機構哈萨克科学院地震研究所[1]機構類型商业、政府機構机构驻地 哈萨克斯坦阿拉木图[2]机构首长主席：阿巴卡诺夫[3]上级机构哈萨克斯坦共...

أنتون روبنشتاين

أنتون روبنشتاين (بالروسية: Антон Рубинштейн)‏    معلومات شخصية الميلاد 16 نوفمبر 1829[1][2]  الوفاة 8 نوفمبر 1894 (64 سنة) [3][4]  بيتيرهوف[5][6]،  وسانت بطرسبرغ[7]  مكان الدفن مقبرة تيخوين  مواطنة الإمبراطورية الروسية  إخوة وأخوات نيكولاي...

 

Cinema of Tunisia

Filmmaking in Tunisia Cinema of TunisiaNaceur Ktari (2000)No. of screens48 (As of July 2022)[1] • Per capita0.2 per 100,000 (2009)[1]Produced feature films (2005–2009)[2]Total4 (average)Number of admissions (2008)[3]Total600,000 The cinema of Tunisia began in 1896, when the Lumière brothers began showing animated films in the streets of Tunis. History The first feature-length movie produced in North Africa, Les Cinq gentlemen maudits (T...

 

Takel (Alat Angkat)

artikel ini tidak memiliki pranala ke artikel lain. Tidak ada alasan yang diberikan. Bantu kami untuk mengembangkannya dengan memberikan pranala ke artikel lain secukupnya. (Pelajari cara dan kapan saatnya untuk menghapus pesan templat ini) Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Januari 2023. Artikel ini...

Pygidium

Posterior body part or shield of crustaceans and some other arthropodsDiagram showing the location of the cephalon, thorax and pygidium of a trilobite. The pygidium (pl.: pygidia) is the posterior body part or shield of crustaceans and some other arthropods, such as insects and the extinct trilobites. In groups other than insects, it contains the anus and, in females, the ovipositor. It is composed of fused body segments, sometimes with a tail, and separated from thoracic segments by an artic...

 

Jabal al-Akrad

Mountain range in Syria Not to be confused with Kurd Mountain. Jabal al-AkradSalma obstacle with the valley, 2014Highest pointElevation400–1,000 m (1,300–3,300 ft)Coordinates35°39′N 36°12′E / 35.650°N 36.200°E / 35.650; 36.200GeographyJabal al-AkradLocation in Syria LocationLatakia, Idlib, Syria Jabal al-Akrad (Arabic: جبل الأكراد Jabal al-Akrād, lit. Mountain of the Kurds) is a rural mountainous region with an elevation that range...

 

All the Rage (Blood on the Dance Floor album)

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: All the Rage Blood on the Dance Floor album – news · newspapers · books · scholar · JSTOR (January 2018) (Learn how and when to remove this template message) 2011 studio album by Blood on the Dance FloorAll the Rage!!Studio album by Blood on the Da...

Esther Neuenschwander

Swiss curler Esther NeuenschwanderCurlerNeuenschwander at the Players Championship 2018Born (1983-09-30) 30 September 1983 (age 40)Zürich, SwitzerlandTeamCurling clubCC Aarau, Aarau, SUICurling career Member Association  SwitzerlandWorld Championshipappearances6 (2006, 2007, 2013, 2019, 2021, 2022)European Championshipappearances4 (2017, 2018, 2019, 2021)Olympicappearances2 (2018, 2022)Grand Slam victories2 (2015 Tour Challenge, 2019 Champions Cup) Medal record Women's Curling...

 

Jennifer Rankine

Australian politician For the Australian poet and playwright, see Jennifer Rankin. Jennifer RankineMinister for Education and Child DevelopmentIn office21 January 2013 – 3 February 2015Preceded byGrace PortolesiSucceeded bySusan CloseMember of the South Australian House of Assemblyfor WrightIn office11 October 1997 – 17 March 2018Preceded byScott AshendenSucceeded byBlair Boyer Personal detailsBorn (1955-09-22) 22 September 1955 (age 68)Mannum, South Australia, Aust...

 

MLW

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Oktober 2022. Museum Kodam VI/MLW adalah sebuah museum yang terletak di Jalan Letjen Suprapto Nomor 04, Kampung Baru Tengah, Balikpapan Barat, Balikpapan, Kalimantan Timur.[1] Museum kodam VI/MLW dijadikan sebagai salah satu warisan budaya oleh Pemerintah In...

Jack Horner (paleontologist)

American paleontologist Jack HornerHorner in 2015Born (1946-06-15) June 15, 1946 (age 77)Shelby, Montana, U.S.CitizenshipUnited StatesAwardsRomer–Simpson Medal (2013)Scientific careerFieldsPaleontologyInstitutionsChapman University, Horner Science Group John Robert Horner (born June 15, 1946) is an American paleontologist most famous for describing Maiasaura, providing the first clear evidence that some dinosaurs cared for their young. In addition to his paleontological discoveries, Ho...

 

Artsadmin

This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article contains content that is written like an advertisement. Please help improve it by removing promotional content and inappropriate external links, and by adding encyclopedic content written from a neutral point of view. (February 2019) (Learn how and when to remove this template message) This article may need to be rewritten to co...

 
Kembali kehalaman sebelumnya